如果你早產過 請警惕心臟病

Premature delivery is tied to increased heart risks in the mother, a review of studies has found.

一項研究綜述稱，母親心臟病風險增加與早產有關。

Pregnancy complications such as pre-eclampsia, pregnancy-induced hypertension and gestational diabetes are recognized risk factors for cardiovascular disease in the mother. But this analysis, published in The European Journal of Preventive Cardiology, found that preterm delivery itself also increases the risk.

妊娠併發症，如先兆子癇、妊娠高血壓綜合徵（妊高徵）和妊娠期糖尿病是公認的母親心血管疾病風險因素。但《歐洲預防心臟病學雜誌》(The European Journal of Preventive Cardiology)上發表的一項分析表明，早產本身也會增加母親心血管疾病發作的風險。

Researchers reviewed 10 large pregnancy studies, with sample sizes ranging from 3,706 to 923,686 women and follow-up periods ranging from 12 to 35 years. All compared women who had premature babies spontaneously — that is, a birth before 37 weeks’ gestation that was not induced for Medical reasons — to women who gave birth to full-term babies. All studies either excluded cases of pre-eclampsia and intrauterine growth restriction, or adjusted for hypertension and pre-eclampsia.

研究人員檢視了10項大規模的妊娠期研究，樣本量在3706至923686人之間，隨訪期從12至35年不等。這些研究比較了有自發性早產史（定義爲並非因醫學原因引產而在妊娠37周前分娩）的婦女與足月生產的婦女，而且，均排除了先兆子癇和宮內發育遲緩病例，或針對妊高徵和先兆子癇進行了校正。

Women with a history of preterm delivery had double the risk for ischemic heart disease, stroke or other cardiovascular disease compared with those without such a history, and the association was independent of other risks. The reasons remain unclear.

具有早產史的婦女發生缺血性心臟病、中風和其他心血管疾病的風險是無早產史的婦女的兩倍，且該相關性與其他風險因素無關。箇中原因尚不清楚。

“I don’t want to scare women who have a premature baby,” said the lead author, Dr. Karst Y. Heida, a gynecology resident at the University Medical Center Utrecht. “But it’s important that we are aware of women who are at increased risk. We’re not saying that if you have a premature baby it means you’re going to have a cardiac event.”

“我無意嚇唬那些有早產史的婦女，”該研究的主要作者，荷蘭烏特勒支大學醫學中心(University Medical Center Utrecht)的婦產科住院醫師博士卡斯特·Y·海達(Karst Y. Heida)說。“但瞭解哪些婦女風險較高非常重要。我們的研究結果並不代表只要你有早產史就一定會發生心臟問題。”