我國科學家發現了可抑制HIV擴散的蛋白質大綱

Chinese scientists have identified a new protein that restricts HIV infection, which could pave way for development of new antivirus drugs.

我國科學家已經發現了一種新的可抑制HIV感染的蛋白質，此發現將爲新的抗病毒藥物的研發奠定基礎。

The protein, P-selectin glycoprotein ligand 1 (PSGL-1), can inhibit HIV reverse transcription and effectively block its viral infectivity, according to the research, published on science journal Nature earlier this month.

本月早些時候發表在科學雜誌《自然》(Nature)上的一項研究表明，這種名爲p-選擇素糖蛋白配體1 (PSGL-1)的蛋白質能夠抑制HIV的逆轉錄，並有效地阻止其病毒感染。

The study, conducted by researchers from universities including Tsinghua University in Beijing, and Fudan University in Shanghai, also showed PSGL-1 can be down regulated by HIV-1 Vpu, an accessory protein of HIV, so it fails to resist HIV infection.

北京清華大學和上海復旦大學研究人員組成的研究小組所發表的研究也表明，HIV的附屬蛋白HIV-1 Vpu對PSGL-1有向下調節作用，所以它未能阻止HIV的傳染。

Further research is underway to develop a drug that can inhibit the HIV protein so PSGL-1 can work to resist HIV.

能夠抑制HIV蛋白的藥物研究正在進一步開展，以便PSGL-1能夠運作起來對抗HIV。